azathioprine$6347$ - traduction vers allemand
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azathioprine$6347$ - traduction vers allemand

CHEMICAL COMPOUND
Azahexal; Azathioprine sodium; Imuran; Azothioprine; Azamun; Azasan; Imurel; C9H7N7O2S; ATC code L04AX01; ATCvet code QL04AX01; Azanin; Ccucol; Imurek; Azathioprine Sodium; Jayempi
  • Two generic azathioprine oral tablets, 50 mg each
  •  TdGTP: thio-[[deoxyguanosine triphosphate]]
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  • The whole process of azathioprine synthesis

azathioprine      
n. Imidazolylderivat (verwendet u.a. als Immunreaktion unterdrückendes Mittel zur Verhinderung von Transplantat Abstoßung) (med.)

Wikipédia

Azathioprine

Azathioprine, sold under the brand name Imuran, among others, is an immunosuppressive medication. It is used for the treatment of rheumatoid arthritis, granulomatosis with polyangiitis, Crohn's disease, ulcerative colitis, and systemic lupus erythematosus; and in kidney transplants to prevent rejection. It is listed by the International Agency for Research on Cancer as a group 1 carcinogen (carcinogenic to humans). It is taken by mouth or injected into a vein.

Common side effects include bone-marrow suppression and vomiting. Bone-marrow suppression is especially common in people with a genetic deficiency of the enzyme thiopurine S-methyltransferase. Other serious risk factors include an increased risk of certain cancers. Use during pregnancy may result in harm to the baby. Azathioprine is in the purine analogue and antimetabolite family of medications. It works via 6-thioguanine to disrupt the making of RNA and DNA by cells.

Azathioprine was first made in 1957. It is on the World Health Organization's List of Essential Medicines. In 2018, it was the 358th most commonly prescribed medication in the United States, with more than 800,000 prescriptions.